Twitching Algorithm
Stepwise algorithm for diagnosing and fixing the cause of eye/muscle twitching: start with urine pH, then trial electrolytes, then assess metabolism/thyroid, then test or trial B vitamins, with molybdenum considered for sulfite control.
Assembled by Cited from Chris Masterjohn's recorded recommendations across multiple sources. It is not an ordered program and was not created or endorsed by them — it's our grouping of what they've said on the record.
Components
13-
Organic (prompted) In a protocol
Check postprandial urine pH; it should fall between 6.4 and 6.8. Below 5s suggests acidity; above 7 suggests alkalinity as a possible twitching factor.
“If it's postprandial, it should be in the 6.4 to 6.8 range
MN▶ 4:10DosagePostprandial target 6.4–6.8CertaintyexplicitrecommendationFirst step: check urine pH (target 6.4–6.8 postprandial) -
Organic (prompted) In a protocol
Use bicarbonate to modulate urine pH upward if too acidic.
“you can modulate that directly with bicarbonate
MN▶ 4:20CertaintyexplicitrecommendationUse bicarbonate if pH too acidic -
Organic (prompted) In a protocol
Use acidic foods/beverages to lower urine pH if too alkaline.
“with acidic foods and beverages
MN▶ 4:25CertaintyexplicitrecommendationUse acidic foods/beverages if pH too alkaline -
Organic (prompted) In a protocol
Trial sodium supplementation around 400 mg to test effect on twitching.
“start with a dose of around 400 milligrams
MN▶ 4:50Dosage~400 mg, titrate up or downCaveatsNeed to titrate to find effectCertaintyhedgedrecommendationElectrolyte trial ~400 mg, titrate -
Organic (prompted) In a protocol
Trial magnesium (~400 mg) for twitching; magnesium clears calcium in muscle, acts as NMDA receptor off-switch.
“magnesium also comes into play as the off switch for NMDA receptors
MN▶ 2:30Dosage~400 mg, titrateCertaintyhedgedrecommendationElectrolyte trial ~400 mg; NMDA off-switch -
Organic (prompted) In a protocol
Calcium may be trialed as an electrolyte for twitching given its role in vesicle release and muscle contraction.
“sodium and potassium and magnesium and calcium
MN▶ 5:00Dosage~400 mg, titrateCertaintyhedgedrecommendationElectrolyte trial -
Organic (prompted) In a protocol
Supplement molybdenum to control sulfite, which enhances glutamate toxicity, especially with high animal protein intake.
“supplementing with molybdenum to control sulfite
MN▶ 3:45CaveatsTakes longer to act than electrolytesCertaintyexplicitrecommendationFor sulfite control, especially high animal protein/low molybdenum -
Organic (prompted) In a protocol
Observe whether things that increase metabolism worsen twitching to identify hypermetabolic causes.
“do things that increase my metabolism increase the twitching?
MN▶ 5:30CertaintyexplicitrecommendationAssess whether boosting metabolism worsens twitching -
Organic (prompted) In a protocol
Measure blood levels of B vitamins if acute interventions don't resolve twitching.
“measure blood levels of B vitamins
MN▶ 6:05CertaintyexplicitrecommendationIf acute factors don't resolve, test B vitamins -
Organic (prompted) In a protocol
If acute factors don't resolve twitching, measure B vitamin levels or trial a B complex.
“just take a B complex and see if that helps
MN▶ 6:10CaveatsSlower to act than electrolytesCertaintyexplicitrecommendationOr just trial a B complex -
Organic (prompted) In a protocol
B6 status matters for glutamate-GABA balance relevant to twitching.
“vitamin B6 is involved in the interchange
MN▶ 1:25Certaintyexplicitoffhand mentionB6 specifically relevant to glutamate/GABA balance