supplement · Tracked item
Nicotinamide riboside (NR)
Every recorded take from the experts Cited tracks — each with the exact quote, source, and timestamp.
◆ Experts divided
3 recommendations across 3 experts · 3 episodes
1 endorse
1 nuanced
1 avoid
Who's on the record
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Organic (prompted) In a protocol Alternative
Bryan trialed NR for 90 days; like NMN, it pegged his intracellular NAD to age-18 levels.
“I did 90 days on NR... both were basically effective
TD▶ 1:13:20DosageTitrate to measured intracellular NADCaveatsMeasure to confirmCertaintyhedgedrecommendation -
Attia remains highly skeptical that NAD precursors offer phenotypic benefit in normal aging individuals.
“Incredibly uninspiring data so far
TP▶ 1:07:00CaveatsOpen to being proven wrong with good dataCertaintyexplicitmild caution -
NAD precursor; raises NAD levels and lowers inflammation in humans; some evidence for ALS function when combined with pterostilbene.
“NR has been taken over the counter…since 2014
LW▶ 13:40Dosage250 mg to 1 g per day; takes 9–10 days to peakCaveatsMany mouse benefits (lower blood sugar, insulin sensitivity, mitochondrial increases) not yet borne out in short human studiesCertaintyhedgedrecommendation