Longevity Biomarker Panel
Attia's recommended set of tests beyond standard labs for longevity-focused risk stratification: ApoB, Lp(a), ApoE genotype, cystatin C, uric acid, homocysteine, fasting insulin.
Assembled by Cited from Peter Attia's recorded recommendations across multiple sources. It is not an ordered program and was not created or endorsed by them — it's our grouping of what they've said on the record.
Components
7-
In a protocol
Measure ApoB to assess all atherogenic particle concentration — a more important cardiovascular marker than LDL-C or HDL-C.
“apob being a more important metric than LDL cholesterol
TT▶ 1:58:00Certaintyexplicitstrong endorsementApoB — primary atherogenic particle measure -
In a protocol
Test Lp(a) at least once — it's a genetically-determined high-risk lipoprotein that informs how aggressively to optimize ApoB.
“knowing lp... will allow you to understand how much more you need to optimize
TT▶ 1:58:10CaveatsCannot be modified, but informs ApoB targetCertaintyexplicitrecommendationLp(a) — at least once -
In a protocol
Know your APOE genotype to understand Alzheimer's risk and motivate preventive measures.
“APOE is one thing for sure. We really do want to know that genotype
TT▶ 1:57:45Certaintyexplicitstrong endorsementAPOE genotype for Alzheimer's risk -
In a protocol
Use cystatin C instead of creatinine to assess kidney function — far more accurate, unaffected by muscle mass.
“creatinine is a joke
TT▶ 1:59:10CaveatsCosts a few dollars more than creatinineCertaintyexplicitstrong endorsementCystatin C instead of creatinine -
In a protocol
Attia includes uric acid in his core biomarker panel.
“Uric acid, homocysteine, insulin, liver function tests
TT▶ 1:59:00CertaintyexplicitrecommendationUric acid -
In a protocol
Attia includes homocysteine in his core biomarker panel.
“Uric acid, homocysteine, insulin
TT▶ 1:59:02CertaintyexplicitrecommendationHomocysteine -
In a protocol
Attia tracks insulin as a core biomarker for metabolic health.
“Uric acid, homocysteine, insulin
TT▶ 1:59:04CertaintyexplicitrecommendationFasting insulin