supplement · Tracked item
Spermidine
Every recorded take from the experts Cited tracks — each with the exact quote, source, and timestamp.
▲ Strong endorse
2 recommendations across 2 experts · 2 episodes
2 endorse
0 nuanced
0 avoid
Who's on the record
-
Organic (prompted)
Polyamine that promotes cellular autophagy and supports mitochondrial integrity in aging brains.
“Spermidine works by cellular autophagy
BG▶ 30:10Dosage1–3.5 mg/day for 3+ monthsCertaintyexplicitrecommendation -
In a protocol
Autophagy inducer; Sinclair takes ~1 g/day in the morning; shown to improve memory in older adults at 1.2 g/day.
“I've added that to my protocol
LW▶ 1:07:10Dosage~1 g/day in the morning (memory study used 1.2 g/day over 3 months)CaveatsSinclair advises the company that makes it (disclosed conflict)Certaintypersonal onlypersonal use