supplement · Tracked item
Rapamycin
Every recorded take from the experts Cited tracks — each with the exact quote, source, and timestamp.
▲ Mostly endorse
2 recommendations across 2 experts · 2 episodes
1 endorse
1 nuanced
0 avoid
Who's on the record
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Organic (prompted)
Attia classifies rapamycin as 'promising' for geroprotection — strong cross-species lifespan data but no definitive human evidence; he takes it himself but prescribes to <10% of patients.
“I'm going to put rapamycin in the promising category
TP▶ 10:40Dosageintermittent dosing (referenced from prior podcasts)CaveatsInsufficient human evidence; only prescribed to patients willing to understand risks; not recommended broadlyCertaintyhedgedpersonal use -
mTOR inhibitor; extends lifespan in every organism tested; potentially toxic and immune suppressive; ~10 mg/week considered for longevity.
“it's extended the lifespan of every organism it's been given to
LW▶ 47:50Dosage~10 mg per week (low, non-immunosuppressive dose)CaveatsCan be toxic; immune suppression at higher doses; not generally availableCertaintyhedgedrecommendation