Sleep Supplement Stack
Hyman's explicitly listed 'most helpful' supplements for sleep, with clear use-cases and cautions.
Assembled by Cited from Mark Hyman's recorded recommendations across multiple sources. It is not an ordered program and was not created or endorsed by them — it's our grouping of what they've said on the record.
Components
6-
In a protocol
Take magnesium glycinate at night to relax the nervous system and support sleep.
“Take magnesium at night, magnesium glycinate or threonine
TD▶ 13:20DosageAt nightCertaintyexplicitstrong endorsementMagnesium glycinate at night - most consistently helpful -
In a protocol Alternative
Magnesium threonate is another preferred form for nighttime sleep support.
“magnesium glycinate or threonine
TD▶ 13:20DosageAt nightCertaintyexplicitrecommendationMagnesium threonate as alternative form -
In a protocol
Take L-theanine, an amino acid from green tea, to promote a calm relaxed state especially if your mind races at night.
“L-theanine is a great option, especially if your mind races at night
TD▶ 21:30CertaintyexplicitrecommendationL-theanine especially if mind races -
In a protocol
Glycine, an amino acid, can support deeper, more restorative sleep and help lower core body temperature.
“glycine. Most people never heard of it, but it's an amino acid
TD▶ 21:40CertaintyexplicitrecommendationGlycine for deeper sleep / lower core body temp -
In a protocol
Use low-dose melatonin only short-term for jet lag or schedule disruption; not for chronic use.
“low dose melatonin and short term only
TD▶ 22:00DosageAs low as 0.5 mg, short-term use onlyCaveatsNot recommended for regular/long-term useCertaintyexplicitrecommendationLow-dose melatonin short-term only for jet lag/travel -
In a protocol
Don't stack sleep supplements without a plan or addressing root causes.
“no random stacking supplements without a plan
TD▶ 22:50CaveatsWork with a practitioner insteadCertaintyexplicitmild cautionCaution: no random supplement stacking without a plan